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Research · Volume 2. Odour, emotion and memory: a review of 119 studies · 8/10

Appendix B. All 277 effect sizes

277 effect sizes extracted from the studies: metric, value, 95% confidence interval, number of studies, sample size and heterogeneity.

#StudyOutcomeMetricValue95% CIkNI²Notes
1Dikeçligil & Gottfried, 2024Variance in perceived guaiacol intensity explained by OR10G4 genotype%15Mainland et al. 2014, cited secondarily in the review; valence >10%
1Dikeçligil & Gottfried, 2024Variance in perceptual space explained by pleasantness%30Khan et al. 2007 (Dravnieks Atlas, 159 odorants), cited secondarily
1Dikeçligil & Gottfried, 2024Prediction of 19 semantic descriptors from cheminformatic features (population)r0.41DREAM Challenge, Keller et al. 2017; individual r = 0.21
4Torske et al., 2022ALE peak in left amygdala, all odours vs odourlessALE0.1271081744Cluster k = 1,163 voxels; −22, 0, −20; ALE metric not in the protocol’s list
4Torske et al., 2022Aversive > Pleasant, right insula/OFCt3.67k = 525 voxels; 36, 20, −8; P95 threshold
4Torske et al., 2022Food > Aversive, left parahippocampal/amygdala/entorhinalt2.75k = 222; −14, −2, −26
4Torske et al., 2022Pleasant > Aversive, left hippocampus/parahippocampal/OFCt2.15k = 158; −20, −8, −22
5Zhou et al., 2021Piriform–hippocampus vs auditory–hippocampus theta synchrony (iEEG)t48t(7), P = 0.0052; 8/8 participants
5Zhou et al., 2021Effect of region on left hippocampal connectivity (olfactory vs visual/auditory/tactile)F25.825F(3,72), P = 1.92e-11; right F = 16.37
5Zhou et al., 2021Connectivity of 7 targets (olfactory vs non-olfactory) with the hippocampusF18.525F(6,144), P = 7.77e-16
5Zhou et al., 2021Anterior > posterior preference, temporal piriformF15.6725F(1,24), P = 0.00059
8Kurian et al., 2021Proportion of odorants antagonising at least one receptor%50Pfister et al. 2020, ~800 odorants, cited secondarily
8Kurian et al., 2021Proportion of mouse ORs expressed (RNA-seq)%98.9Ibarra-Soria/Saraiva, cited secondarily
11Kehl et al., 2024Mean amygdala firing across 15 odours vs standard valence scale (Toet 2020)r0.5615Spearman, P = 0.03; N = 15 odours
11Kehl et al., 2024Hippocampal decoding vs correct identification rate across sessionsr0.527P = 0.0076; PC r = 0.14, amygdala r = 0.06 not significant
11Kehl et al., 2024Amygdala: liked vs disliked odours (firing)z2.9130Wilcoxon, P = 0.004; N = 130 neurons
11Kehl et al., 2024Proportion of PC neurons modulated by odour%39.517± 4.7% per session; N = 17 sessions
11Kehl et al., 2024Repetition suppression in the amygdala over 8 presentationsz-4.5130P = 6.9 × 10⁻⁶
12Sagar et al., 2023RSA neural–perceptual similarity in OFCr0.123Pooled Spearman, P < 0.0001; molecular rm = 0.077
12Sagar et al., 2023RSA fine-grained perceptual code in OFCr0.0833Raw rc = 0.063; rf > rc P < 0.0001
12Sagar et al., 2023RSA neural–perceptual similarity in the amygdalar0.0593P < 0.0001; rm = 0.050
13Sagar et al., 2026RSA valence in OFCβ0.5693Standardised β, P < 0.001; β metric not in the protocol’s list
13Sagar et al., 2026Trial-wise salience decoding in OFCr0.1574400N = trials; valence r = 0.145
13Sagar et al., 2026Aversive > appetitive pleasantness decoding in the amygdalaz4.584P < 0.001; PirC z = 4.263
13Sagar et al., 2026Cross-decoding appetitive↔aversive in OFC (negative sign = salience code)r-0.0682197P = 0.002
19Soudry et al., 2011Depression in olfactory dysfunction after acute rhinitis (Faulcon 1999)%60“nearly 60%” had some degree of depression in the first months; N not stated
20Saive et al., 2014Odour recognition at short intervals (Engen & Ross 1973)%73% correct
22Yang et al., 2025Difference in endpoints/voxels across 8 amygdala nucleiF9.305725One-way ANOVA, df = 7, p = 6.6e-10
22Yang et al., 2025Endpoints of olfactory vs non-olfactory nucleit7.3125df = 99, p = 7.1e-11
22Yang et al., 2025Number of unique streamlines, olfactory vs non-olfactoryt3.725paired, df = 49 (left/right separately), p = 5.4e-4 (Figure 3 caption gives p = 2.0e-5)
23Noto et al., 2021k=2 clustering of olfactory nuclei, right hemispherez4.2725permutation, P = 2.0e-6
23Noto et al., 2021k=2 clustering of olfactory nuclei, left hemispherez4.7925permutation, P = 1.7e-6
23Noto et al., 2021k=3 clustering matching anatomical nucleiz6.0525minimum z
24Buchanan et al., 2003Odour–name matching false alarms across 3 groupsF5.640F(2,37), p = 0.007, η² = 0.23
24Buchanan et al., 2003Response bias C for odour–name matching across 3 groupsF3.540F(2,37), p = 0.041, η² = 0.16
24Buchanan et al., 2003Odour–name matching d′, pooled lobectomy vs controlst1.740t(38), p<0.05
24Buchanan et al., 2003Group × old/new interaction on familiarity scoresF6.240F(1,38), p = 0.017, η² = 0.14
24Buchanan et al., 2003Residual right amygdala volume vs name-matching false alarmsr0.42p<0.05; right hippocampus r = 0.46
27Li & Wilson, 2023Proportion of piriform voxels shifting tuning to CS+ on day 9 (You 2022)%20>20%; absent on day 1
29Tong et al., 2014Improvement in discrimination learning, block 1 day 2 vs day 1t7.56t(8), p < 0.001; mice
32Hackländer et al., 2019Emotional intensity of odour-cued vs other-cued AMsd0.47109 experiments/10 data points; t(9) = 2.33, p = .022
32Hackländer et al., 2019Feeling of being brought backd0.477t(6) = 2.36, p = .028
32Hackländer et al., 2019Less rehearsed (Rare)d0.524t(3) = 3.54, p = .019
32Hackländer et al., 2019Pleasant valence of the memoryd0.35108 experiments/10 points; t(9) = 3.43, p = .004
32Hackländer et al., 2019Vividnessd0.110t(9) = 2.02, p = .037; possibly overestimated
32Hackländer et al., 2019Cue effectiveness (proportion of trials yielding an AM)d-0.58estimated d ≈ .50 against odours (M .63 vs .76; Wilcoxon Z = 2.52, p = .012); negative sign…
32Hackländer et al., 2019Decade × modality interaction on the proportion of memories by ageF16.25F(2,8), p = .002, ηp² = .80
34Dejou et al., 2026Earliest childhood odour memories from events repeated > 5 times (human survey)%73.164713.4% repeated 2–5 times; 13.4% once
34Dejou et al., 2026Still periodically re-encounter childhood odours (human survey)%82647
34Dejou et al., 2026Pleasantness of reported vs unreported odour descriptorst2.01146t(98.9), p = 0.024; 51 vs 95 descriptors
35Yang et al., 2021Theta phase separation between sequence positions, correct vs incorrect trials, anterior hippocampust7.326t5, p < 0.001; PCx t5 = 5.97, p = 0.002
35Yang et al., 2021PCx–AH theta PLV during replayt8.685t4, p < 0.001
35Yang et al., 2021Proportion of replay before correct vs incorrect responses%75775% vs 53%; Fisher p < 1e-4
35Yang et al., 2021Correlation of replay with % correct (bootstrap)r[0.12; 0.15]only CI95 [0.12, 0.15] reported
36Szychowska et al., 2025Olfactory vs visual spatial memorySMD-0.48[-0.77; -0.19]771.09Glass, random effects; z = −3.22, p = 0.0013; PI95 [−1.15, 0.19]
37Huang et al., 2026OB volume vs olfactory functionr[0.15; 0.93]23range of r across studies (not a CI); 20/23 significant
37Huang et al., 2026Reduced OBV and/or OSD vs controls%905045/50 studies
37Huang et al., 2026DTI indices vs olfactory functionr[0.31; 0.52]3range of r for the 3 significant studies (not a CI); 1 not significant
37Huang et al., 2026Cortical thickness near the OS vs TDI in congenital anosmia (Ottaviano 2015)r-0.51p = 0.001
38Smitka et al., 2012Right hippocampal volume vs odour thresholdr0.21117Pearson, p = 0.02
38Smitka et al., 2012Right hippocampal volume vs odour threshold, controlling for ager0.18117partial r(114), p = 0.049
41Keller et al., 2007Androstadienone EC50, S84N vs RT (in vitro)%EC50 nearly 20 times lower than RT (ratio ~20×); absolute values only in the figure
41Keller et al., 2007WM allele frequency (R88W/T133M)%15.4412allele frequency 0.154
43Stephan et al., 2012Single-cell response termination τ (IBMX)MD466ms; 612 ± 53 (KO) − 146 ± 13 (WT); calculated from the note’s data
43Stephan et al., 2012Ratio τ(Na⁺-free)/τ(Ringer)%WT 4.5 ± 0.6-fold vs KO 1.08 ± 0.03-fold, P < 0.001
43Stephan et al., 2012% of cells firing to the second pulse at a 0.25 s interval%45WT ~45%; KO 0% (up to a 1 s interval)
44Reisert & Zhao, 2011% of WT OSNs firing to the second pulse at a 0.25 s interval%50~50%; Song 2008; n = 19–49 OSNs, χ² P = 0.007
46Gottfried, 2010% of piriform neurons (APC/PPC) responding sub-additively to mixtures%[40; 60]about 40–60% sub-additive; 20–40% supra-additive (rodent imaging);…
47Wilson & Sullivan, 2011Proportion of LEC units responding to odours%35.212845/128 (~one third); % calculated from the note’s data
49Howard et al., 2009Prediction of inter-individual perceptual structure from PPC patternsr0.444F₁,₂₄ = 18.84; P = 0.001; leave-one-subject-out
49Howard et al., 2009PPC Procrustes goodness-of-fit (neural vs perceptual)%0.534goodness-of-fit (lower = better), outside the 95% CI of the shuffled distribution; actual metric is…
49Howard et al., 2009Within- > between-odour correlation in OFC (Exp. 1)t5.46T₅; P = 0.0029
49Howard et al., 2009Category classification in PPC (Exp. 2)t2.344T₃; P = 0.050 (right at the threshold)
50Zelano et al., 2011PPC template strength vs behavioural accuracyr0.6412P = 0.02; between individuals
50Zelano et al., 2011Same−different target difference in PPC vs accuracyr0.6612P = 0.01
50Zelano et al., 2011APC encodes the target before the odour (same > different target)t6.312T11; P < 0.0001
51Jiang et al., 2017Four-class decoding accuracy in PPC/amygdala%464SD 7.3%; chance 25%; in 4 participants the PPC was the best electrode
51Jiang et al., 2017% of trials with a theta peak in the inhalation phase (odour vs air)%78.47air 55.6% ± 6.4%; Z = 2.366, p = 0.018
51Jiang et al., 2017Regression of theta on electrode positionF30.69F(1,240); r² = 0.21; p < 0.001
53Grabenhorst et al., 2007Anterolateral OFC BOLD vs pleasantness ratingsr0.9114[40, 52, −6], Z = 2.69, p = 0.042
53Grabenhorst et al., 2007Medial OFC BOLD vs pleasantness ratingsr0.8814[4, 46, −14], Z = 2.41, p < 0.05
53Grabenhorst et al., 2007Piriform BOLD vs intensityr0.8614[−18, 4, −16]; with pleasantness r = −0.15, p = 0.60
53Grabenhorst et al., 2007Pleasantness ratings across the three odoursF41.814F(2,26), p ≪ 0.001
54Bao et al., 2019ERC grid-pattern strength vs prediction performancer0.4825robust regression, p = 0.03; one outlier > 3 SD
54Bao et al., 2019Slope of the ERC pattern effect by angular deviationt-2.6525t24, p = 0.014
55Bushdid et al., 2014 (with Meister 2015; Gerkin & Castro 2015)Discrimination resolution (majority of participants) — critical % overlap%51.1726pairwise 57.43%; regression y = −0.81x + 91.45
55Bushdid et al., 2014 (with Meister 2015; Gerkin & Castro 2015)Regression of discrimination rate on % overlap (per participant)%-0.8126slope coefficient; intercept 91.45
56Lee et al., 2023% of molecules for which the GNN is closer to the panel mean than the median panellist%53323RF baseline 41%
56Lee et al., 2023Proportion of chemical samples with significant odour-active impurities%31.5[27.4; 35.6]95% CI; estimated from GC-MS/GC-O
56Lee et al., 2023Accuracy on odd-one-out triplets (GNN vs RF)%5041RF 19%; binomial p < 0.01
56Lee et al., 2023Mean cross-validation AUROC of the GNNAUC0.8950005-fold CV, ~5,000 molecules
58Sela & Sobel, 2010Proportion of people noticing manipulation of ambient odour (Lorig 1992)%3.2933/93; % calculated from the note’s data
60Zald & Pardo, 1997Left amygdala rCBF vs unpleasantnessr-0.5120pooled 12 sulfide pairs + 8 UPSIT pairs; p < 0.05; lower score = more unpleasant
60Zald & Pardo, 1997Left amygdala rCBF vs unpleasantness (first pair only)r-0.5612p < 0.05
60Zald & Pardo, 1997Left OFC rCBF vs unpleasantnessr-0.4620p < 0.05
60Zald & Pardo, 1997Covariation of left OFC rCBF ↔ left amygdalar0.6520p < 0.005
60Zald & Pardo, 1997Left amygdala activation, sulfide vs odourlessz5.210Talairach (−34, −4, −11)
60Zald & Pardo, 1997Right amygdala activation, sulfide vs odourlessz510Talairach (26, −1, −14)
62Winston et al., 2005Amygdala BOLD: concentration × odour type interactionF4.717df (2.0; 31.7); p = 0.017
62Winston et al., 2005Amygdala BOLD high − low, unpleasant odourt4.1170.23 % ± 0.058; p < 0.001
62Winston et al., 2005Amygdala BOLD high − low, pleasant odourt2.3170.14 % ± 0.061; p = 0.017
62Winston et al., 2005Amygdala BOLD high − low, neutral odourt0.005170.0001 % ± 0.057; p = 0.50
63Li et al., 2008Within-pair vs between-pair pattern correlation (method check, before conditioning)f0.66p < 0.005; metric “f” as in the note, not in the standard list; N not established (…
64Krusemark et al., 2013Change in valence (neutral − negative) vs increase in anxietyr-0.6114p < 0.05
64Krusemark et al., 2013Change in valence of neutral odours relative to negative odourst-3.0314t(13); p < 0.01
64Krusemark et al., 2013Right pgACC BOLD vs increase in anxietyr0.7712p = 0.002; conjunction
64Krusemark et al., 2013Total DCM modulation by neutral odours vs increase in anxietyr0.612p = 0.04
64Krusemark et al., 2013Neutral-odour detection RT (advantage over air) after vs before anxietyt2.114t(13); p = 0.05; −457 → −314 ms
65Iravani et al., 2021RSA OB gamma – valence (250–325 ms)r0.619controlling for intensity; p < 0.010
65Iravani et al., 2021RSA OB beta – valence (≈800 ms)r0.6519p < 0.014
65Iravani et al., 2021PAM at 0.5 s, unpleasant vs pleasant odour differencet3.24[0.06; 0.23]44t(174); p < 0.001; CI is for the PAM difference; BF10 = 3.32; preregistered
65Iravani et al., 2021Leaning away from negative odourst2.4744t(174); p < 0.007 one-sided
66Root et al., 2014PI for TMT avoidance when OB axons are inactivated in CoA (light on)PI-7.911vs −65 ± 3.4 without light; PI = (P − 25)/0.25, non-standard metric
66Root et al., 2014PI for 2-phenylethanol attraction when inactivated in CoAPI-8.36vs +48 ± 3.2 without light
66Root et al., 2014PI on optogenetic activation of TMT-tagged CoA neuronsPI-496± 4.6
66Root et al., 2014PI on optogenetic activation of 2-phenylethanol-tagged CoA neuronsPI424± 6.4
67Chrea et al., 2009Canonical correlation of emotion factors ↔ odour qualityr0.83p < 0.001; NC1
67Chrea et al., 2009Correlation of Relaxation ↔ Refreshment factors (GEOS)r0.832256CFA latent correlation, Table 6
71de Groot & Smeets, 2017Fear chemosignalling, all outcomes (after removing outliers, r_high)g0.36[0.31; 0.41]12402.8Q(18) = 18.52, p = 0.422; abstract figure; N = 1,240 is the N of the full analysis set
71de Groot & Smeets, 2017Fear chemosignalling, overall, r_lowg0.36[0.27; 0.46]124031.1Q(20) = 29.03, p = 0.087
71de Groot & Smeets, 2017Fear chemosignalling, overall, r_highg0.34[0.26; 0.42]124055.6Q(20) = 45.09, p = 0.001
71de Groot & Smeets, 2017Fear chemosignalling, after removing outliers, r_lowg0.4[0.32; 0.48]0Q(18) = 16.48, p = 0.559
73Mujica-Parodi et al., 2009Left amygdala BOLD STRESS > EXERCISE (original)t4.816Z = 3.68; p(SVC) = 0.02; MNI (−16, −10, −18)
73Mujica-Parodi et al., 2009Left amygdala BOLD STRESS > EXERCISE (replication)t5.2116Z = 3.88; p(SVC) = 0.008; MNI (−27, −6, −12)
73Mujica-Parodi et al., 2009Slope σ of the psychometric function for angry-face discrimination (stress vs exercise)F8.314p = 0.01; increase of ~43 %
73Mujica-Parodi et al., 2009Donor cortisol before vs after skydivingt7.15400.229 → 0.584 µg/dL; p < 0.001
74de Groot et al., 2020Axillary sweat volume by fear-intensity group (linear contrast)F24.8536F(1,35); p < 0.001; η² = 0.42
74de Groot et al., 2020Composite fear score (CFS) vs sweat volumer0.636Spearman; p < 0.001
74de Groot et al., 2020Leave-one-out classification of fear intensity%83.333630/36, vs chance 33 %
74de Groot et al., 2020Decay of the PID signal over timeeta2_partial0.53RM-ANCOVA F(34,68) = 2.23, p = 0.003; non-standard metric
76Zelano et al., 2016RT for fearful-face recognition, inhalation vs exhalation (nasal breathing)t-2.6421t(20); p = 0.016; ~28 ms
76Zelano et al., 2016Route × emotion × phase interaction on RTF4.7738F(1,36); p = 0.036
76Zelano et al., 2016Retrieval accuracy, inhalation vs exhalation (nasal breathing)t2.8511t(10); p = 0.017
76Zelano et al., 2016Correlation of piriform slow oscillations with respiration, nasal breathing (P7)r0.64p = 0.002; mouth breathing r = 0.09 (n.s.)
76Zelano et al., 2016Amygdala delta power during inhalation vs fearful-face RT (P8)r-0.4p = 0.05; 24 trials
78Bagur et al., 2021% freezing, OBX vs sham (significant blocks)NR0.77note only states “effect size 0.77 and 0.97”, metric type not stated; RM-ANOVA group p = 0.038
78Bagur et al., 2021% freezing, OBX vs sham (second block)NR0.97metric type not stated in the note
78Bagur et al., 2021% freezing, ChR2 stimulation of OB at 13 Hz vs no stimulationNR2.08p = 0.016; metric type not stated in the note
78Bagur et al., 20214 Hz power vs micro-movementsr-0.56p = 2.3e−54
78Bagur et al., 2021Proportion of dmPFC neurons phase-locked to OB 4 Hz during freezing%45100vs ~23 % during activity; χ² = 9.82, p = 0.0017; N = neurons
79Daniels & Vermetten, 2016Prevalence of odour-triggered panic attacks in the past month (refugees, Hinton 2004)%45100cited study; 58 % of these had flashbacks
79Daniels & Vermetten, 2016Proportion with ≥50 % reduction in PTSD severity after HOC (Abramowitz & Lichtenberg 2010)%5836cited study; no control group
79Daniels & Vermetten, 2016Olfactory bulb volume after childhood maltreatment vs controls (Croy 2013)%80cited study; “~80 %”
80Rasch et al., 2007location memory (spatial), odour-cue SWS vs vehicleg0.69[0.19; 1.18]18Exp.1, 7.5 h sleep; recalculated by Hu 2020; Z=2.717, p=0.007
80Rasch et al., 2007finger tapping, SWSg0.08[-0.52; 0.37]18p=0.734; note records it as positive but the CI is skewed negative — minus sign possibly lost
80Rasch et al., 2007location memory, REMg0.05[-0.51; 0.4]17Exp.3, p=0.813; sign possibly lost
80Rasch et al., 2007finger tapping, REMg0.21[-0.67; 0.25]17p=0.366; g lies outside the CI → almost certainly −0.21 (minus sign lost)
80Rasch et al., 2007TMR SWS vs wake (fMRI exp)g0.64[0.05; 1.22]12Exp.5, 1.5 h sleep in the scanner, p=0.033; flagged as an outlier by Hu
82Shanahan et al., 2018vmPFC reactivation ↔ memory benefit (over time)r0.7[0.42; 0.86]1890% CI; FIR correlation peak
82Shanahan et al., 2018vmPFC, cued categories onlyr0.6118r(16)=0.61, p=0.01
82Shanahan et al., 2018posterior fusiform, cued categories onlyr0.7218r(16)=0.72, p<0.001
82Shanahan et al., 2018vmPFC cluster, reactivation–memoryt7.5318t(16), p_FWE=0.01, MNI [6,46,−12]
82Shanahan et al., 2018less forgetting for the cued categoryz1.718Wilcoxon, p=0.04 one-tailed
83Hu et al., 2020TMR overall, all measuresg0.29[0.21; 0.38]21220047191 experiments; Z=6.711
83Hu et al., 2020TMR after trim-and-fillg0.18[0.06; 0.3]17 studies added, p=0.003
83Hu et al., 2020TMR three-parameter selection modelg0.13[0.06; 0.21]p=0.001
83Hu et al., 2020TMR with odoursg0.32[0.15; 0.5]32372equivalent to sounds; Q(2)=0.688
83Hu et al., 2020TMR during SWSg0.27[0.2; 0.35]174147170 experiments
83Hu et al., 2020TMR during N2g0.32[0.04; 0.6]131656 experiments, p=0.026
83Hu et al., 2020TMR during REMg0.06[-0.31; 0.18]15142p=0.616; CI skewed negative → true g possibly −0.06
83Hu et al., 2020TMR during wakefulnessg0.07[-0.09; 0.23]30366p=0.394
83Hu et al., 2020TMR for skill learning (NREM)g0.51[0.37; 0.65]2322910 experiments
83Hu et al., 2020TMR for language learning (NREM)g0.4[0.14; 0.65]131589 experiments
83Hu et al., 2020TMR for emotional memory (NREM)g0.11297n.s., p=0.366
83Hu et al., 2020TMR for fear memory (NREM)g0.02497n.s.; disregarding direction g=0.44, p=0.004
84Chu & Downes, 2002number of new detailed sentences in phase 2, 4 conditionsχ²16.7240df=3, p<0.001; congruent odour 120 vs label 71
84Chu & Downes, 2002pain ratings (absolute change), 3 groupsχ²19.3242Kruskal–Wallis df=2, p<0.001
84Chu & Downes, 2002pleasantness ratings, 3 groupsχ²17.5242Kruskal–Wallis df=2, p<0.001
87Yeshurun et al., 2009memory for first vs second association on day 8F6.416F(1,15), p<0.023; 50.5% vs 34.5%
87Yeshurun et al., 2009unpleasant first association vs secondt3.5316t(15), p<0.003; 56.3% vs 28.8%
87Yeshurun et al., 2009left hippocampus, memory for first vs second associationF9.6916F(1,14), p<0.007, odours only
87Yeshurun et al., 2009day-1 activity predicts memory after 1 week (odours)F14.616F(1,14), p<0.002
88Gottfried et al., 2004right posterior piriform, hits > CRz3.3415p<0.001 uncorrected; MNI 30,3,−12 (sign inferred from anatomy)
88Gottfried et al., 2004right anterior hippocampus, hits > CRz2.8315p<0.005 uncorrected; y,z signs inferred from anatomy
88Gottfried et al., 2004pleasant vs neutral hitsF6.715F(1,14), p<0.05; 0.89 vs 0.84
89Dahmani et al., 2018odour identification ↔ 4/8 VM errors, spatial learnersr-0.57[-0.77; -0.33]24bootstrap BCa 95% CI, partial correlation (sex)
89Dahmani et al., 2018odour identification ↔ 4/8 VM errors, whole groupr-0.37[-0.52; -0.21]57
89Dahmani et al., 2018odour identification ↔ % landmarks found (wayfinding)r0.26[0.06; 0.45]57
89Dahmani et al., 2018right hippocampal volume ↔ odour identification (spatial)r0.32[0.03; 0.6]23
89Dahmani et al., 2018left mOFC thickness ↔ odour identification (spatial)r0.33[0.02; 0.64]23
89Dahmani et al., 2018odour scores, mOFC+ vs controlsMD-3.7[-6.02; -1.12]29mOFC+ n=9 (1 case excluded from the odour analysis) vs 20 controls; bootstrap difference
90Igarashi et al., 2014proportion of dCA1 cells phase-locked to LEC 20–40 Hz, T1→T5%17.4from 7.9% to 17.4%, P<0.005
90Igarashi et al., 2014proportion of LEC cells phase-locked to dCA1, T1→T5%24.4from 13.3% to 24.4%, P<0.005
90Igarashi et al., 2014LEC spike phase-locking with learningF21F(4,383), P<0.001
91Lee et al., 2021proportion of successful learning sessions, fan-cell inhibition vs controls%2510controls 90.9%; binomial p=4.1×10⁻¹⁰
91Lee et al., 2021proportion of correct sessions, dopamine inhibition vs controls%54.38controls 92.4%; binomial p=2.5×10⁻¹¹
91Lee et al., 2021fan cells expressing D1R%422185/441 cells, n=2 mice
92Sullivan et al., 2000direction of odour–shock learning by age (group × age)F9.29F(2,54), P<0.001
92Sullivan et al., 2000maintenance of preference PN9→PN10F17.94F(1,33), P<0.001
92Sullivan et al., 2000amygdala 2-DG, training × ageF3.37F(2,35), P<0.05
93Moriceau & Sullivan, 2006odour–shock learning PN12–15, with vs without the motherF25.56332F(3,28), P<0.0001; N inferred from df
93Moriceau & Sullivan, 2006corticosterone into the amygdala with the mother present → avoidanceF35.362F(2,20), P<0.0001
93Moriceau & Sullivan, 20062-DG in the lateral amygdala nucleusF27.94F(4,20), P<0.0001
94Schaal et al., 2000negative facial expressions to anise odour, exposed vs unexposedd-1.72[-2.906; -0.527]124recalculated by PLoS ONE 2023; p≤0.005
94Schaal et al., 2000head orientation towards anise odourd1.29[0.324; 2.25]124PLoS ONE 2023; p=0.009
94Schaal et al., 2000mouthing (Schaal 2000 + Wagner 2019 pooled)d1.035[0.164; 1.906]2p=0.02; not specific to this paper
94Schaal et al., 2000head orientation, pooled 4 studies of flavour exposure via the maternal dietd1.24[0.56; 1.91]440PLoS ONE 2023; homogeneous; p<0.001
94Schaal et al., 2000negative expressions, pooled 4 studiesd-0.87[-2.39; 0.66]478.7PLoS ONE 2023; n.s.
96Devanand et al., 2015conversion to AD, UPSIT Q1 vs Q4HR10.33[4.55; 23.49]757discrete-time survival model
96Devanand et al., 2015conversion to AD per UPSIT point (lower)HR1.099[1.067; 1.131]757unadjusted; after covariates 1.072 (1.036–1.109)
96Devanand et al., 2015conversion to AD per UPSIT point, adjustedHR1.072[1.036; 1.109]757sex, age, language, education, SRT-TR, function
96Devanand et al., 2015cognitive decline per UPSIT pointRR1.067[1.04; 1.095]732after covariates 1.065 (1.034–1.095)
96Devanand et al., 2015cognitive decline per UPSIT point, people without MCIRR1.096[1.06; 1.135]498after covariates 1.089 (1.050–1.130)
96Devanand et al., 2015AUC of UPSIT predicting cognitive declineAUC0.638732SRT-TR 0.513; p<0.001
96Devanand et al., 2015AUC of UPSIT predicting ADAUC0.65757SRT-TR 0.73; combined 0.77
97Olofsson et al., 20215-year mortality risk, anosmia vs normalHR3Pinto 2014 via review: “3 times higher”; approximate metric
97Olofsson et al., 2021mortality risk per additional correctly identified odour%-6Wilson 2011 via review, ~4 years
100Ball et al., 2020CMAI agitation (Ballard 2002, lemon balm)MD-11.1[-20; -2.2]171cluster RCT, 8 care homes, moderate certainty
100Ball et al., 2020CCMAI agitation (Lin 2007, lavender)MD-5.13[-13.21; 2.95]170not significant
100Ball et al., 2020NPI (Ballard 2002)MD-15.8[-24.4; -7.2]171moderate certainty
100Ball et al., 2020NPI (Burns 2011, lemon balm)MD2.8[-5.84; 11.44]163moderate certainty, no benefit
100Ball et al., 2020NPI (Fujii 2008, lavender)MD-9[-17.89; -0.11]128low certainty
100Ball et al., 2020NPI (Lin 2007, lavender)MD-6.64[-10.85; -2.43]170low certainty
100Ball et al., 2020NPI (Takahashi 2020, cedar)MD-4.26[-9.46; 0.94]136CI includes 0
100Ball et al., 2020QoL Blau (Burns 2011)MD19[-23.12; 61.12]163not significant
100Ball et al., 2020MMSE (Fujii 2008)MD1[-4.19; 6.19]128not significant
100Ball et al., 2020ADAS-cog (Takahashi 2020)MD-0.36[-6.6; 5.88]136not significant
100Ball et al., 2020Barthel ADL (Burns 2011)MD-0.5[-1.79; 0.79]163not significant
100Ball et al., 2020Caregiver burden J-ZBI (Takahashi 2020)MD-6.27[-12.29; -0.25]136low certainty
101Donelli et al., 2019Anxiety, all scales (inhaled lavender vs all controls)g-0.73[-1; -0.46]24168285MA6; excluding 3 outliers g −0.54 [−0.73; −0.36] I² 65%
101Donelli et al., 2019Anxiety, all scales (inhaled, only RCTs not at high RoB)g-0.64[-0.82; -0.47]5350most robust estimate
101Donelli et al., 2019Anxiety, high-anxiety situations (inhaled)g-0.8378excluding outlier g −0.67 I² 55%; mild anxiety not significant
101Donelli et al., 2019HAM-A (Silexan 80 mg vs placebo)MD-2.9[-4.86; -0.95]5117374MA1; excluding Kasper 2010 I² 28%
101Donelli et al., 2019Zung SAS (Silexan 80 mg vs placebo)MD-2.62[-4.84; -0.39]345117MA2
101Donelli et al., 2019STAI-S (inhaled vs usual care/none)MD-5.99[-9.39; -2.59]1290195MA3; excluding high RoB −3.67 p=0.05 I² 53%
101Donelli et al., 2019STAI-T (inhaled vs usual care/none)MD-8.14[-14.44; -1.84]419691MA4; excluding Mirbastegan −4.81 [−8.32; −1.31] I² 59%
101Donelli et al., 2019Systolic blood pressure (inhaled vs none/sham)MD-1.91[-3.32; -0.51]63980mmHg; r=0.5; 7 comparisons; inconclusive
101Donelli et al., 2019Anxiety, all scales (lavender massage)g-0.66[-0.97; -0.35]644861MA7; cannot be separated from the massage
102Kasper et al., 2014HAMA (Silexan 160 mg vs placebo)MD4[1.9; 6.1]1256positive sign = greater reduction with Silexan; FAS 121+135; p<0.001 one-sided
102Kasper et al., 2014HAMA (Silexan 160 mg vs placebo)d0.51256Cohen’s d
102Kasper et al., 2014HAMA (Silexan 80 mg vs placebo)MD2.8[0.9; 4.8]1270FAS 135+135; p=0.003
102Kasper et al., 2014HAMA (Silexan 80 mg vs placebo)d0.371270Cohen’s d
102Kasper et al., 2014HAMA (paroxetine 20 mg vs placebo)d0.211267not significant in the FAS
102Kasper et al., 2014HAMA (Silexan 160 mg vs paroxetine)MD2.8[0.7; 4.9]1253FAS
102Kasper et al., 2014HAMA response rate ↓≥50% (160 mg vs placebo)%60.31121placebo 37.8%
104Lin et al., 2019Sleep quality (aromatherapy vs control)g1.103[0.813; 1.393]3191.216Egger p=0.004, Begg p=0.008 — publication bias; estimate may be inflated
105Kiecolt-Glaser et al., 2008PANAS positive affect, time × odourF4.43156F(6,240), p<0.001; lemon > lavender, water
105Kiecolt-Glaser et al., 2008Norepinephrine, time × odourF2.35156F(10,456), p=0.01
105Kiecolt-Glaser et al., 2008Candida DTH by odourF4.47154F(2,92), p=0.014; water > lavender; 2 participants excluded for lacking DTH
105Kiecolt-Glaser et al., 2008Negative affect decreasing over timeOR2.8156time effect only, p=0.001
107de Araujo et al., 2005Pleasantness of test odour: cheddar label vs body odour labelt6.68112t(11); difference of 0.76 points on the −2..+2 scale
107de Araujo et al., 2005Pleasantness of clean air: cheddar label vs body odour labelt4.1112t(11), p<0.001
107de Araujo et al., 2005rACC/mOFC BOLD correlated with pleasantnessz4.35112MNI [16,46,−4], p<0.05 corrected
109Perl et al., 2016NREM delta power after vs before odour%9.79127SD 18.0; t(26)=3.22, P<0.005
109Perl et al., 2016NREM slow-spindle power after vs before odour%5.16127SD 7.81; t(26)=3.91, P<0.001
109Perl et al., 2016K-complexes per trial after vs before odour (N2)t0.14134t(33), P>0.55; BF01 = 6.61 supporting H0; note gives 95% CI −0.104 to −0.004 (inconsistent…
110Hummel et al., 2009Proportion with clinically meaningful TDI improvement (>6 points), training group%28140vs 6% in the non-training group (n=16); from a secondary source
111Sorokowska et al., 2017TDI after olfactory trainingg1.1[0.459; 1.734]11879Q = 172.73; I² NR
111Sorokowska et al., 2017Identificationg0.83[0.264; 1.402]131005Q = 200.66
111Sorokowska et al., 2017Discriminationg0.89[0.498; 1.298]10788Q = 57.06
111Sorokowska et al., 2017Thresholdg0.34[0.103; 0.569]12951Q = 32.37
111Sorokowska et al., 2017TDI, post-infectious subgroupg1.52vs 0.45 in other groups; Q = 4.34, p = 0.04
111Sorokowska et al., 2017Identification, post-infectious + post-traumatic subgroupsg1.54vs 0.29
112Pieniak et al., 2022Proportion with clinical improvement after 6 months of OT (Qiao 2019)%41.711.7% after 1 month; 26.7% after 3 months
112Pieniak et al., 2022Proportion with clinical improvement after 56 weeks of OT (Konstantinidis 2016)%711vs 37% without intervention
113Kattar et al., 2021Clinically meaningful TDI improvement (>5.5 points), OT vs controlOR2.77[1.67; 4.58]4post-viral olfactory dysfunction; I² NR
114Kohli et al., 2016BDI–TDI correlation in patients with olfactory dysfunctionr-0.3493260weighted by sample size, p<0.001
114Kohli et al., 2016SS Identification: depression vs controlsMD-0.41360calculated from 12.57 vs 12.98 (152/208); p<0.0001
114Kohli et al., 2016SS Threshold: depression vs controlsMD-0.47291calculated from 6.31 vs 6.78 (122/169); p=0.0005
114Kohli et al., 2016Prevalence of depression (BDI) in anosmia after upper respiratory infection%76125Jung 2014; CRS 40%
116Spangenberg et al., 1996Store evaluation (scented vs unscented)F5.511298F(6,291), p<0.0001
116Spangenberg et al., 1996Approach behaviour/intentions (multivariate)F3.131298F(12,285), p<0.001
116Spangenberg et al., 1996Intention to visit the storeMD0.7412984.20 → 4.94; p=0.003
116Spangenberg et al., 1996Perceived shopping time%-131298660.8 s vs 576.0 s (≈ −85 s); p=0.021; % calculated by the note’s reader
117Roschk & Hosseinpour, 2020Recallr0.177291299adjusted r; +11.3%
117Roschk & Hosseinpour, 2020Spendingr0.051528150ns; +3.2%
117Roschk & Hosseinpour, 2020Shopping satisfactionr0.144403095+9.2%
117Roschk & Hosseinpour, 2020Environmental qualityr0.1221056709+7.8%
117Roschk & Hosseinpour, 2020Product evaluationr0.1211326878+7.7%
117Roschk & Hosseinpour, 2020Time elusivenessr0.111131336+7.1%
117Roschk & Hosseinpour, 2020Purchase intentionr0.105492849+6.7%
117Roschk & Hosseinpour, 2020Mood – activationr0.097756469+6.2%
117Roschk & Hosseinpour, 2020Mood – valencer0.0881208099+5.6%
117Roschk & Hosseinpour, 2020Lingeringr0.078332762+5.0%
118Krishna et al., 2010Recall of product attributes by odour (Exp. 1)F39.651151F(2,141), η² = 0.36
118Krishna et al., 2010Recall of scented vs unscented tissues after 2 weeks (Exp. 2)MD0.6311434.65 → 5.28; F(1,135) = 5.111, η² = 0.05
118Krishna et al., 2010Retention rate after 2 weeks, familiar odour%76.81unscented 26.6%; novel odour 91.8%

Scientific reference material, not medical advice. Figures are redrawn from published data, not copied from the original figures. GRADE and risk-of-bias ratings are the compilers’ own. Every number traces back to detailed reading notes on each paper.